Evidence-Based Focused Review FDG PET-CT in follicular lymphoma: a case-based evidence review
نویسندگان
چکیده
A 52-year-old woman develops right neck lymphadenopathy in the absence of systemic symptoms. Excisional biopsy specimen shows grade 1-2 follicular lymphoma (FL). Physical examination reveals a cluster of 1to 2-cm right cervical nodes but no other abnormalities. Lactate dehydrogenase is 400 U/L (normal: 140-210 U/L), b-2 microglobulin is 4.1 mg/mL (normal: 0-2.5 mg/mL), and a complete blood count with differential is normal. 18-Fluorodeoxyglucose (FDG) positron emission tomography (PET) with computed tomography (CT) is performed, showingFDGavid lymphadenopathy above and below the diaphragm, ranging in size from 1.2 to 6 cm. Three FDG-avid lymph nodes measure more than 3 cm. A single 6-cm pelvic node has a maximum standardized uptake value (SUVmax) of 22, and other SUVs range from 6 to 8. An absence of FDG marrow uptake is noted. How should these PET-CT findings be integrated into further evaluation, prognostication, and treatment recommendations for this patient with FL? Should repeat PET-CT be performed on completion of therapy?
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